Information About Specific Medications :

Prednisolone (Wysolone) :

Prednisone is a corticosteroid that helps prevent and treat rejection of transplanted organs. It may be used for long-term (perhaps lifetime). Tacrolimus (Pangraf/Prograf) 9immunosuppression or, in higher doses, for treatment of rejection. They should be taken with meals or just after meals , as they cause gastric irritation. It should be taken as a single dose in the morning, before 11am.

Common side effects of prednisolone are :

  • Stomach irritation occasionally leading to ulcer. To prevent this are given .
  • Weight gain caused by increase in your appetite. You should eat wisely and maintain a steady weight.
  • Your face may become more rounded.
  • Skin changes like acne, thinning of skin, easy bruising.
  • An increase in blood sugar
  • Eye problems - If your eye become sore or you have problems with your vision let your doctor know.
  • The above side effects improve when the dose is reduced.


Mycophenolate Mofetil (CellCept):

Fights rejection by decreasing the number of white blood cells the immune system produces. The most frequent side effect seen is stomach upset ( eg. Diarhoea and vomiting) or effects relating to a reduced ability by the body to fight infections. It is given either in form of capsules or syrup.

Azathioprine (Imuran, Azoran) :

Azathioprine (Imuran, Azoran) :Azathioprine is given with other immunosuppressants to help prevent rejection of the new kidney. It may be used for long-term (perhaps lifetime) immunosuppression. It should be taken after a meal to reduce the chance of stomach upset. It may cause an increase in your liver function tests .